Magnetic stem cells… a new treatment option for osteoarthritis?

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Magnetic stem cells… a new treatment option for osteoarthritis?



Kamei and colleagues published a study where they used magnetized stem cells to heal cartilage defects in a mini-pig model. The problem with stem cell treatment has been the difficulty of delivering cells to and retaining them in target tissues long enough to repair or regenerate local tissues.
They used an external magnet to keep the stem cells applied to the cartilage defects in place. The regenerated cartilage was evaluated by arthroscopic surgery at 6 and 12 weeks and histological and ultrasound evaluation at 12 and 24 weeks. The magnetized stem cells had no adverse effect on chondrogenic differentiation, and they repaired cartilage defects.

The authors concluded the clinical application of this novel stem cell delivery system was a potential therapeutic option for treating cartilage defects and may be more applicable throughout the body than traditional methods.
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