Stem Cell Therapy Following Meniscus Knee Surgery May Reduce Pain, Restore Meniscus

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Stem Cell Therapy Following Meniscus Knee Surgery May Reduce Pain, Restore Meniscus



A single stem cell injection following meniscus knee surgery may provide pain relief and aid in meniscus regrowth, according to a novel study appearing in the Journal of Bone and Joint Surgery.
In the first-of-its-kind study, “Adult Human Mesenchymal Stem Cells (MSC) Delivered via Intra-Articular Injection to the Knee, Following Partial Medial Meniscectomy,” most patients who received a single injection of adult stem cells following the surgical removal of all or part of a torn meniscus, reported a significant reduction in pain. Some patients─24 percent of one MSC group and 6 percent of another─experienced at least a 15 percent increase in meniscal volume at one year. There was no additional increase in meniscal volume at year two.
“The results demonstrated that high doses of mesenchymal stem cells can be safely delivered in a concentrated manner to a knee joint without abnormal tissue formation,” said lead study author C. Thomas Vangsness, Jr., MD. “No one has ever done that before.” In addition, “the patients with arthritis got strong improvement in pain” and some experienced meniscal regrowth.
Comment: While this is an encouraging report, the uncontrolled nature of the study fails to give us much more insight than we already have.

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