Stem cells and osteoarthritis… the role of insulin-like growth factor

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Stem cells and osteoarthritis… the role of insulin-like growth factor



When it comes to alternatives to knee replacement surgery, regenerative medicine techniques aimed at repairing cartilage have looked primarily at mesenchymal stem cells supplemented by various growth factors. One such growth factor is insulin-like growth factor. It is capable by itself of promoting cartilage growth and repair. Using it in conjunction with stem cells, it appears to be an important “player” in the restoration of cartilage. Various studies looking at insulin-like growth factor by itself have shown mixed results. However, it appears to be an important adjunctive factor for cartilage regrowth.
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