What are the sources of stem cells in the adult?

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What are the sources of stem cells in the adult?



There a number of different sources of SCs in the adult. Usually, adult SCs tend to differentiate into the tissue of origin. These include:
Hematopoietic cells which become different types of blood cells.
Mesenchymal cells which lead to connective tissue. These are the ones that have found the most utility so far in conditions such as osteoarthritis.
Neural SCs that become cell types found in the central and peripheral nervous system.
Digestive system cells that form various cells in the gut.
Skin SCs that lead to various parts of the skin and subcutaneous tissue.
Some recent experiments suggest that adult SCs can be programmed to become cells of a different organ system. This process is called “transdifferentiation.” What causes this to occur and the exact limitations invoked on the adult stem cell as far as how much they can differentiate is still open to conjecture.
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